Python-based SNP annotation software
TRAMS, also known as Tool for Rapid Annotation of Microbial SNPs, is a program for functional annotation of genomic SNPs which is available to download as a single file executable for WINDOWS users with limited computational experience and as a Python script for Mac OS and Linux users.
TRAMS needs only a tab delimited text file containing SNP locations, reference nucleotide and SNPs in different strains along with a reference genome sequence in standard GenBank or EMBL format.
TRAMS annotates SNPs as synonymous, non-synonymous or nonsense. Non-synonymous SNPs in start and stop codons are separated as non-start and non-stop SNPs, respectively. SNPs in overlapping features are annotated separately for each feature and multiple nucleotide polymorphisms (MNPs) within a codon are combined prior to annotation.
Operating system:Windows XP / XP 64 bit / Vista / Vista 64 bit / 7 / 7 64 bit
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